Publications
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2014
Imaging Morphology and Function of Cortical Microglia. in Optical Imaging of Neocortical Dynamics vol. 85 209-223 (Springer Protocols, 2014). doi:10.1007/978-1-62703-785-3_13.
Longitudinal PET/MRI reveals -amyloid deposition and rCBF dynamics, and connects vascular amyloidosis to quantitative loss of perfusion. Nat Med doi:10.1038/nm.3734 (2014).
Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes. Nat Methods 175-182 (2014).
Impairment of in vivo calcium signaling in amyloid plaque-associated microglia. Acta Neuropathologica 127, 495-505 (2014) doi:10.1007/s00401-013-1242-2.
Network-wide dysregulation of calcium homeostasis in Alzheimer's disease. Cell & Tissue Research 427-438 (2014).
2013
Imaging microcircuit function in healthy and diseased brain. in Experimental Neurology vol. 242 41-49 (2013).
Microglial calcium signaling in the adult, aged and diseased brain. Cell Calcium 159-169 (2013).
In vivo functional properties of juxtaglomerular neurons in the mouse olfactory bulb. Frontiers in Neural Circuits 7, 1-23 (2013).
2012
In vivo functional imaging of the olfactory bulb at single cell resolution. in Neuronal Network Analysis vol. 67 21-43 (2012).
Sound-evoked network calcium transients in mouse auditory cortex in vivo. Journal of Physiology 590, 899-918 (2012).
High resolution in vivo imaging of microglia using a versatile non genetically-encoded marker. European journal of immunology 2193-2196 (2012) doi:10.1002/eji.201242436.
Two-Photon Chloride Imaging Using MQAE In Vitro and In Vivo. Cold Spring Harb Protoc. 778-785 (2012).
Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells. Proc Natl Acad Sci USA 18150-18155 (2012).
2011
Two-photon chloride imaging using MQAE in vitro and in vivo. in Imaging in Neuroscience: A Laboratory Manual 623-632 (Cold Spring Harbor Laboratory Press, 2011).
Microglial calcium signal acts as a rapid sensor of single neuron damage in vivo. Biochimica et biophysica acta - Molecular Cell Research 1014-1024 (2011).
Two-Photon Imaging of Neural Networks in a Mouse Model of Alzheimer's Disease. in Imaging in Neuroscience: A Laboratory Manual 999-1010 (Cold Spring Harbor Laboratory Press, 2011).
Two-photon imaging of neural networks in a mouse model of Alzheimer's disease. Cold Spring Harb Protoc 1206-1216 (2011).
2010
Disruption of the olivo-cerebellar circuit by Purkinje neuron-specific ablation of BK cannels. Proceedings of the National Academy of Sciences of the United States of America 107, 12323-12328 (2010).
Intracellular calcium signalling in Alzheimer's disease. J Cell Mol Med 14, 30-41 (2010).
In vivo two-photon calcium imaging using multi-cell bolus loading technique. Cold Spring Harb Protoc pdb prot5482 (2010).
In vivo Ca2+ imaging of the living brain using multi-cell bolus loading technique. in Calcium Measurement Methods vol. 43 205-220 (Humana Press, New York, 2010).
Monitoring Calcium Levels With Genetically Encoded Indicators. in Neuromethods series: Calcium measurements in neural cells vol. 101-118 (Humana Press, New York, 2010).
2009
Wide-field and two-photon imaging of brain activity with voltage- and calcium-sensitive dyes. Methods Mol Biol 489, 43-79 (2009).
Sparsification of neuronal activity in the visual cortex at eye-opening. Proc. Natl. Acad. Sci. USA 106, 15049-15054 (2009) doi:10.1073/pnas.0907660106.
2008
Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease. Science 321, 1686-1689 (2008).